Jan 16, 2013· Using Micronization to Reduce API Particle Size. A mill can be enclosed inside a barrier isolator for processing highly potent drugs. In addition, jet mills can be operated in sterile conditions by integrating the mill in an isolator or a restricted access barrier system (RABS) as needed, notes Gianola.
Micronizer ® Jet Mill. No company has sold and engineered more fluid energy mills than the Micronizer ® by Sturtevant. The Micronizer ® operates by particleonparticle attrition to grind without the introduction of heat or wear into the grinding process and is capable of particle reduction to 250nm.
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Micronization is the process of reducing the average diameter of a solid material's particles. Traditional techniques for micronization focus on mechanical means, such as milling and grinding. Modern techniques make use of the properties of supercritical fluids and manipulate the principles of solubility.
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Filter press. Suspension Hot calcined product Moist filter cake Cooled product. The filter cake is gently transported into the granulator cage by two intermeshing, horizontal screws. There, slowly rotating tools pass the cake through a screen plate without pressure, thus splitting up the cake in the process.
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Center of Excellence for Micronization. These superfine particles result in Gaussian distribution curves with superior reproducibility. The process is conducted at ambient conditions due to the instantaneous pressure drop of the grinding gas within the milling chamber, cooling the colliding particles which makes jetmilling an ideal technology for sensitive pharmaceutical ingredients.
Industrial Wax solutions for every process. Utilisation of the FischerTropsch process together with state of the art fractionation, micronisation and blending facilities enables Performance Chemicals to produce superlative products targeted to satisfy the needs of ink makers in every application area as well as intermediate wax grinders, dispersion or compound producers.